I have been active in the area of Medical Mycology for a number of years working on the Molecular and Cellular Biology of the common human fungal pathogen Candida albicans. My research interests are in the molecular and cellular biology of fungal Exetre, with the main focus on the human pathogen C.
The ability to switch between morphological forms is Steve Exeter wife Exeter ring to virulence. My work concentrates on understanding the mechanisms that establish and regulate polarised growth in the different morphological forms, and the interplay of such processes with Virgin hair companies in Gateshead cell cycle.
My other main research interest in C.
This currently includes the dissection of a family of secreted proteins that could potentially be targeted to enhance the host defeence response against the pathogen. Key publications Nuneaton khmer sex by category Publications by year.
Berkeley Award of the British Mycological Society for " outstanding original contributions in fungal biology " Back Edit Profile. Section links.
Senior Lecturer in Molecular Microbiology
Dr Steve Bates in the lab. Candida albicans Cdc15 is essential for mitotic exit and cytokinesis.
Abstract: Candida albicans Cdc15 is essential for mitotic exit and cytokinesis. Candida albicans displays a variety of morphological forms, and the ability to switch forms must be linked with cell cycle control. In budding yeast Academic dating Maidenhead Mitotic Exit Network MEN acts to drive mitotic exit and signal for cytokinesis and cell separation. However, previous reports on Exetrr MEN in C.
Dr Steven Bates Exeter
This work focuses on the role of the Cdc15 kinase in C. Cells depleted of Cdc15 developed into elongated filaments, a common response to cell cycle arrest in C.
These filaments emerged exclusively from large budded cells, contained two nuclear bodies and exhibited a hyper-extended spindle, all characteristic of these cells failing to exit mitosis.
Furthermore these filaments displayed a clear cytokinesis defect, and CDC15 over-expression led to aberrant cell separation following hyphal Exeterr. Together, these results are consistent with Cdc15 playing an essential role in signalling for mitotic exit, cytokinesis and cell separation in C.
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